The French agency that originally voiced concerns about the use of diacerein is also further pushing for the ban of the drug claiming that any possible benefits are "weak". The article listed that many of the cases where individuals experienced diarrhea lead to further complications, including liver problems. Other countries where diacerein is not available is the United States, Canada, Britain, or Australia. The review committee believes diacerein should be suspended "Until the production of studies highlighting its benefits, profits in a specific population". This prompts the idea of what constitutes a drug being so disadvantaged that it is worthy of being banned. Because for example Ja3ked a pre-workout supplement contains a controversial ingredient 1,3 Dimethylamylamine that has caused death to at least 3 people deaths around the world. This deadly concoction has been banned in England yet it is still available to purchase in the United States. So it prompts my question and inquisitiveness regarding what constitutes drugs being banned.
References:
http://www.medscape.com/viewarticle/814067
This shows how the frequencies of side effects and their severity can limit it's life on the shelves. It is also interesting to see the different guidelines that countries have about banning medications. As was mentioned with the work out supplement how it being linked to 3 deaths is cause for England to ban it but not other places. When I googled diacerein I had to dig deep for information about side effects, aside from diarrhea (which usually was the only one listed). This lack of info was surprising to me for it being banned (and getting pushed to be banned) in so many places!
ReplyDeleteWell as a previous jack3d user, the stuff worked. After I hear deaths on the new from using the product i stopped. I dont think the FDA really regulates what being sold until the certain ingredient in the drug cause death and the public is getting concern about using the product. For example the new compound which are in those supplements is "aegeline" which is supposedly the new drug that cause liver failure in the market.
ReplyDeleteIn class I was also interested in the side effects of diacerein to treat symptoms of osteoarthritis and why it was banned in the United States. Madeline had briefly mentioned one of the symptoms was diarrhea, but this article has also linked diacerein with liver damage. The liver damage is most likely the result of long-term use of diacerein. This explains why this drug has been banned in the United States and also in other countries. Diacerein is a drug in which you risk developing liver damage, but you benefit from reducing the symptoms of osteoarthritis.
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