Friday, November 22, 2013

HSV-1 and -2, the culprit behind ß-Amyloid plaques in Alzheimer's Disease?!

Researchers at the University of Manchester's Faculty of Life Sciences have investigated the effect that the common Herpes Simplex Virus has on the brain. Their research has found that over 90% of the viral DNA manifests within ß-amyloid proteins and instigates the growth of the ß-amyloid sheaths in the brain's of patients with Alzeheimer's Disease. HSV-1 and -2 are neurotropic and neuroinvasive viruses, meaning that they are able to remain in the body by becoming dormant in the cell bodies of neurons, hiding from the immune system. According to the researchers, during the dormant stage of the HSV infection, the viruses cause enough damage to disintegrate the neuronal cells. Upon disintegration, they release amyloid, which further develop into sheaths when even more neuronal cells are destroyed. The team hypothesizes that antiviral drugs aimed to inhibit the effects of the virus could also inhibit the plaque formations caused by this virus.


Here is the link to the article:
http://www.sciencedaily.com/releases/2008/12/081207134109.htm

1.) University of Manchester. "Cold Sore Virus Linked To Alzheimer's Disease: New Treatment, Or Even Vaccine Possible." ScienceDaily, 7 Dec. 2008. Web. 22 Nov. 2013.

9 comments:

  1. This is an interesting link between Alzheimer's and HSV. It would be a good study to see how HSV affects human diseases such as Alzheimer's since the majority of the American population is infected with HSV 1.

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    Replies
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  2. Wow, I think this is a really interesting article. I was shocked to learn about these long term effects of the HSV virus. After learning about Alzherimer's it is amazing to think that an antiviral treatment, if further research supports this data, could inhibit a major cause of this disease!
    Although after thinking more about this treatment, I do not think that this method would be effective at reversing damage already done by Alzheimmer's disease.

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  3. I never knew what neurotropic or neuroinvasive viruses were "hiding" from the immune system so thank you for placing that information in there when you discussed how they function. This is just a very interesting, yet scary, article because of the fact that such a high percentage of people have HSV, whether it is active or not, and makes me wonder if this makes a difference as well.

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  4. Thanks for sharing this article it was really interesting. I never really thought about the possibility thought about genetic predisposition having a direct effect on viral migration/progression? It will be interesting to see what genes they might link to this event and what possible treatments may arise to discourage it from happening.

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  5. What can i say about him i am very grateful to see i am finally cured from this HSV2, it have been going to about 1 year and 6 month when i have this sickness i have try different means to get my self cure but
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  6. What can i say about him i am very grateful to see i am finally cured from this HSV2, it have been going to about 1 year and 6 month when i have this sickness i have try different means to get my self cure but
    nothing work out, i can stand and say today with the help of herbal medicine and Dr. vicent there is cure to HSV 2 i ask him how all this work so he explain to me very well that the
    herbal need to be taking twice a day morning and evening, there is going to be soap for bathing too, and the amount it cost, so i was so very happy to hear such i quickly email the doctor for the herbal in 4
    days time i have the herbal medicine in my country USA and the doctor write along with the instruction how to applied the medicine i am very happy , you can just email my doctor now for the herbal medicine
    through his email: vicentspelltemple@gmail.com

    whats app number of the doctor +2348129050649

    And he also have cure to the following sickness

    HIV/AIDS
    HPV
    CANCER
    ALS

    And if you which to talk to me and get more information about cure
    through this email:jamesveronica550@gmail.com

    ReplyDelete
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